San Francisco 49ers
NFL • NFC West
Research odds for all upcoming San Francisco 49ers games. Browse opening spreads and live betting lines for their full schedule.
Latest San Francisco 49ers Betting News
49ers News: A magnificent weekend for a big beautiful trade, ideally a lineman - Niners Nation
Niners Nation · Jun 20
San Francisco 49ers Could Still Trade Former First-Round Pick, Pro Bowl Player - Yahoo Sports
Yahoo Sports · Jun 22
NFL Announces 49ers 2026 Training Camp Dates, Joint Practices - San Francisco 49ers
San Francisco 49ers · Jun 22
Ranking the 10 absolute worst draft picks 49ers made under John Lynch - Niner Noise
Niner Noise · Jun 21
Upcoming San Francisco 49ers Game Lines
- 49ersSan Francisco 49ersN/AN/AN/A@ChargersLos Angeles ChargersN/AN/AN/AThu 8/20, 10:00PM ETSPREADTOTALMONEY
- 49ersSan Francisco 49ers+3.5-110U 48.5-105+165@RamsLos Angeles Rams-3.5-110O 48.5-115-200Thu 9/10, 8:35PM ETSPREADTOTALMONEY
- DolphinsMiami Dolphins+10.5-110U 46.5-110+425@49ersSan Francisco 49ers-10.5-110O 46.5-110-575Sun 9/20, 4:25PM ETSPREADTOTALMONEY
- CardinalsArizona CardinalsN/AN/AN/A@49ersSan Francisco 49ersN/AN/AN/ASun 9/27, 4:05PM ETSPREADTOTALMONEY
- BroncosDenver Broncos+2.5-110U 46.5-110+114@49ersSan Francisco 49ers-2.5-110O 46.5-110-135Sun 10/4, 4:25PM ETSPREADTOTALMONEY
- 49ersSan Francisco 49ers+3.5-110U 48.5-110+170@SeahawksSeattle Seahawks-3.5-110O 48.5-110-205Sun 10/11, 4:25PM ETSPREADTOTALMONEY
- CommandersWashington Commanders+5.5-110U 50.5-110+205@49ersSan Francisco 49ers-5.5-110O 50.5-110-250Mon 10/19, 8:15PM ETSPREADTOTALMONEY
- 49ersSan Francisco 49ers-4.5-110U 47.5-110-230@FalconsAtlanta Falcons+4.5-110O 47.5-110+190Sun 10/25, 1:00PM ETSPREADTOTALMONEY
- RaidersLas Vegas Raiders+8.5-110U 46.5-110+340@49ersSan Francisco 49ers-8.5-110O 46.5-110-440Sun 11/8, 4:05PM ETSPREADTOTALMONEY
- 49ersSan Francisco 49ers+1.5-115U 52.5-110+100@CowboysDallas Cowboys-1.5-105O 52.5-110-120Sun 11/15, 4:25PM ETSPREADTOTALMONEY
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