San Francisco 49ers
NFL • NFC West
Research odds for all upcoming San Francisco 49ers games. Browse opening spreads and live betting lines for their full schedule.
Latest San Francisco 49ers Betting News
San Francisco 49ers' 2026 practice squad tracker - Niners Wire
Niners Wire · Aug 31
49ers Practice Squad Tracker: The potential Week 1 punt returner signs - ninersnation.com
ninersnation.com · Aug 31
49ers Talk: Instant analysis of San Francisco 49ers' final 53-man roster - nbcsportsbayarea.com
nbcsportsbayarea.com · Aug 30
Man poses as a 49ers player to defraud women, authorities say - NBC Bay Area
NBC Bay Area · Aug 26
Upcoming San Francisco 49ers Game Lines
- 49ersSan Francisco 49ers+3.5-110U 48-106+165@RamsLos Angeles Rams-3.5-110O 48-110-200Thu 9/10, 8:35PM ETSPREADTOTALMONEY
- DolphinsMiami Dolphins+10.5-110U 46.5-110+470@49ersSan Francisco 49ers-10.5-110O 46.5-110-650Sun 9/20, 4:25PM ETSPREADTOTALMONEY
- CardinalsArizona Cardinals+11.5-110U 46.5-110+470@49ersSan Francisco 49ers-11.5-110O 46.5-110-650Sun 9/27, 4:05PM ETSPREADTOTALMONEY
- BroncosDenver Broncos+2.5-110U 46.5-110+114@49ersSan Francisco 49ers-2.5-110O 46.5-110-135Sun 10/4, 4:25PM ETSPREADTOTALMONEY
- 49ersSan Francisco 49ers+3.5-110U 48.5-110+170@SeahawksSeattle Seahawks-3.5-110O 48.5-110-205Sun 10/11, 4:25PM ETSPREADTOTALMONEY
- CommandersWashington Commanders+5.5-110U 50.5-110+200@49ersSan Francisco 49ers-5.5-110O 50.5-110-245Mon 10/19, 8:15PM ETSPREADTOTALMONEY
- 49ersSan Francisco 49ers-4.5-110U 47.5-110-218@FalconsAtlanta Falcons+4.5-110O 47.5-110+180Sun 10/25, 1:00PM ETSPREADTOTALMONEY
- RaidersLas Vegas Raiders+8.5-110U 46.5-110+330@49ersSan Francisco 49ers-8.5-110O 46.5-110-425Sun 11/8, 4:05PM ETSPREADTOTALMONEY
- 49ersSan Francisco 49ers+1.5-115U 52.5-110+100@CowboysDallas Cowboys-1.5-105O 52.5-110-120Sun 11/15, 4:25PM ETSPREADTOTALMONEY
- VikingsMinnesota Vikings+4.5-115U 46.5-110+160@49ersSan Francisco 49ers-4.5-105O 46.5-110-192Sun 11/22, 8:20PM ETSPREADTOTALMONEY
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